MODERN LOOK ON RESISTANCE TO PLATINUM IN PATIENTS WITH THE SEROUS OVARIAN CANCER
DOI:
https://doi.org/10.30888/2663-5712.2025-33-02-029Keywords:
ovarian cancer, treatment, platitum resistance, biomarkersAbstract
The study was aimed to determine the platinum-resistance biomarkers in patients with ovarian cancer. 29 platinum-resistant patients with verified serous ovarian cancer of IIIA-IIIC stages were examined, who received 6 courses of adjuvant chemotherapy withReferences
Epidemiology Working Group Steering Committee, Ovarian Cancer Association Consortium Members of the EWG SC, in alphabetical order:, Doherty JA, Jensen A, Kelemen LE, Pearce CL, Poole E, Schildkraut JM, Terry KL, Tworoger SS, Webb PM, Wentzensen N. Current Gaps in Ovarian Cancer Epidemiology: The Need for New Population-Based Research. J Natl Cancer Inst. 2023 Oct 1; 109(10).
Doherty JA, Peres LC, Wang C, Way GP, Greene CS, Schildkraut JM. Challenges and Opportunities in Studying the Epidemiology of Ovarian Cancer Subtypes. Curr Epidemiol Rep. 2017 Sep;4(3):211-220
Rybin, A., A. Varabina, and M. Broshkov. ""Epidemiology and management of ovarian cancer based on the clinical experience of the southern region of Ukraine." Georgian Medical News 288 (2019): 32-36.
Rybin A, Dubinina V, Kuznetsova O. Personalized managing of the patients with serous ovarian cancer. InINTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 2016 Sep 1 (Vol. 26, pp. 35-35). TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA: LIPPINCOTT WILLIAMS & WILKINS.
Kolesnik O.O., Rybin A.I. Predicting the effectiveness of treatment for ovarian cancer patients. Current issues in paediatrics, obstetrics and gynaecology. – 2017. – No. 2. – pp. 40–47. DOI 10.11603/24116-4944.2017.2.8043.
Kolesnik O.O., Rybin A.I. Personalised treatment of ovarian cancer patients. Hospital Surgery. Journal named after L. Ya. Kovalchuk. – 2017. - No. 2 (78). – Pp. 5-12. DOI 10.11603/2414-4533.2017.2.7951.
Ткаченко О.І., Рибін А.І. Кузнецова О.В. Проспективне дослідження клінічної ефективності диференційованого лікування раку яєчників. Одеський медичний журнал. – 2017. - № 6. – С. 45-51.
Bondar, O. V., Rybin, A. I., Maximovskyi, V. E., Kuznetsova, O. V., & Alieva, S. O. (2023). Optimizimg of management of the ovarian cancer patients with peritoneal carcinomatosis. Oncology, 25(3), 222-228. DOI: https://doi.org/10.15407/oncology.2023.03.222.
Rybin A. I., O. V. Kuznetsova, and V. E. Maximovsky. "Modern strategies of surgical treatment of patients with pelvic canceromatosis caused by the ovarian cancer. Visnyk morsʹkoyi medytsyny 2020; 2 (87): 55–61. DOI http://dx.doi.org/10.5281/zenodo.3967728.
Rybin A. (2022). Results of personalised treatment of ovarian cancer in patients with peritoneal carcinomatosis // Reproductive Health of Women, (7), 35–40. https://doi.org/10.30841/2708-8731.7.2022.272470.
RYBIN, A., MAKSYMOVSKYI, V., KUZNETSOVA, O. and ZAMYSHLYAK, V. Personalised treatment of patients with advanced ovarian cancer: comparative analysis of surgical approaches. Journal of Education, Health and Sport. Online. 30 June 2025. Vol. 83, p. 64576. DOI 10.12775/JEHS.2025.83.64576.
MAKSYMOVSKYI, V., RYBIN, A. and ZAMYSHLYAK, V. Quality of life in patients with advanced ovarian cancer under personalised treatment: the impact of HIPEC. Journal of Education, Health and Sport. Online. 11 August 2025. Vol. 84, p. 64751. DOI 10.12775/JEHS.2025.84.64751.
Rybin AI, Maksymovskyj VY, Pyrogov VV, Demidchik RY, Varabina AO. Comparative study of quality of life, adverse effects after cytoreduction and HIPEC in stage IIIA-IIIC ovarian cancer. J Educ Health Sport [Internet]. 2018 Oct. 31 8(10):412-7. DOI http://dx.doi.org/10.5281/zenodo.2456541
Rybin A.I. The role of proteomic and genetic predictors of survival in ovarian cancer patients. Clinical Oncology, 2016, No. 3 (23), pp. 46-48.
Prevention of pathological changes in the mammary glands in patients after surgery for uterine fibroids / S.G. Bugaysov, A.I. Rybin, A.E. Suprun // Oncology. — 2007. — Vol. 9, No. 2. — Pp. 129–132. https://nasplib.isofts.kiev.ua/handle/123456789/20479.
Rybin A. I., Lysenko M. A., Rysina A. I. Features of the sanogenesis system in patients with ovarian cancer resistant to platinum-based chemotherapy. Collection of scientific works of the Association of Obstetricians and Gynaecologists of Ukraine. 2014. 1-2. 251-254.
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