CELL DEATH IN HUMAN PATHOLOGY

Authors

  • Olga Kovalyova Department of General Practice-Family Medicine and Internal Diseases, Kharkiv National Medical University https://orcid.org/0000-0003-3410-6623
  • Vadym Shapkin Department of General Practice-Family Medicine and Internal Diseases, Kharkiv National Medical University https://orcid.org/0000-0002-6784-1811
  • Svitlana Ivanchenko Department of General Practice-Family Medicine and Internal Diseases, Kharkiv National Medical University https://orcid.org/0000-0001-8721-2724

DOI:

https://doi.org/10.30888/2663-5712.2024-23-00-023

Keywords:

apoptosis, autophagy, necrosis, necroptosis, pyroptosis, ferroptosis.

Abstract

An analytical review of the present article is devoted to the aspects of cell death with emphasis on biochemical, morphological, molecular and cellular mechanisms its development, modulation and progression. The triggers of apoptosis, necrosis, necroptosi

Metrics

Metrics Loading ...

References

Chan F.K., Luz N.F., Moriwaki K. Programmed necrosis in the cross talk of cell death and inflammation. Annu Rev Immunol. 2015; 33:79-106. doi: 10.1146/annurev-immunol-032414-112248.

Berghe T.V., Linkermann A., Jouan-Lanhouet S. Et al. Regulated necrosis: the expanding network of non-apoptotic cell death pathways. Nature Reviews Molecular Cell Biology 2014; 15. 2: 135–147 doi: 10.1038/nrm3737.

Chen G.Y., Nuñez G. Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol. 2010; 10: 826–837. doi: 10.1038/nri2873.

Negroni A., Cucchiara S., Stronati L. Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal Homeostasis Mediators Inflamm. 2015; 2015: 250762. doi: 10.1155/2015/250762.

Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J Cancer 1972; 26: 239–257. doi: 10.1038/bjc.1972.33.

Galluzzi, L., Vitale I., Aaronson, S.A. et al. Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death. Cell Death Differ. 2018; 25: 486–541. doi: 10.1038/s41418-017-0012-4.

Locksley R.M., Killeen N., Lenardo M.J. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell. 2001 Feb 23;104(4):487-501. doi: 10.1016/s0092-8674(01)00237-9

Günther C., Buchen B., He G. W., et al. Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways. Gut. 2015; 64(4):601–610. doi: 10.1136/gutjnl-2014-307226.

Pasparakis M. Necroptosis and its role in inflammation. Nature. 2015; 517(7534):311–320. doi: 10.1038/nature14191.

Khoury M.K., Gupta K., Franco S. et al. Necroptosis in the Pathophysiology of Disease. Am J Pathol. 2020 ;190(2):272-285. doi: 10.1016/j.ajpath.2019.10.012.

Rathinam V.A.K., Vanaja S.K., Fitzgerald K.A. Regulation of inflammasome signaling. Nature Immunology. 2012; 13. 4:333–342. doi: 10.1038/ni.2237.

Miao E.A Rajan J.V., Aderem A. Caspase-1-induced pyroptotic cell death Immunological Reviews. 2011; 243: 206–214. doi: 10.1111/j.1600-065X.2011.01044.x.

Kohsuke Tsuchiya Inflammasome-associated cell death: Pyroptosis, apoptosis, and physiological implications Microbiol Immunol. 2020;64(4):252-269. doi: 10.1111/1348-0421.12771.

Stockwell B.R., Friedmann A., Bayir J.P. et al. Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease. Cell 2017: 171: 273–285. doi: 10.1016/j.cell.2017.09.021.

Chen X., Li J., Kang R. Et al. Ferroptosis: Machinery and regulation. Autophagy. 2020;17:2054–2081. doi: 10.1080/15548627.2020.1810918.

Cao J.Y., Dixon S.J. Mechanisms of ferroptosis. Cell. Mol. Life Sci. 2016; 73: 2195–2209. doi:10.1007/s00018-016-2194-1 .

Dixon S.J., Lemberg K.M., Lamprecht M.R. et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060–1072. doi: 10.1016/j.cell.2012.03.042

Ursini F., Maiorino M. Lipid peroxidation and ferroptosis: The role of GSH and GPx4. Free Radic. Biol. Med. 2020; 152:175–185. doi: 10.1016/j.freeradbiomed.2020.02.027.

Xie, Y., Hou, W., Song, X. et al. Ferroptosis: process and function. Cell Death Differ. 2016; 23: 369–379 doi: 10.1038/cdd.2015.158.

Mizushima N., Levine B., Cuervo A.M. et al. Autophagy fights disease through cellular self-digestion. Nature. 2008; 451.7182:1069–1075. doi: 10.1038/nature06639.

Ryter S.W., Mizumura K., Choi A.M.K. The impact of autophagy on cell death modalities. International Journal of Cell Biology. 2014; ID 502676:1-12 12 doi: 10.1155/2014/502676.

Nunes T., Bernardazzi C., de Souza H.S. Cell death and inflammatory bowel diseases: apoptosis, necrosis, and autophagy in the intestinal epithelium. BioMed Research International. 2014; ID 218493: 2-12. doi: 10.1155/2014/218493. Epub 2014 Jul 14. doi: 10.1155/2014/218493.

Engedal N., Proikas-Cezanne T., Maria C. et al. Transautophagy: Research and Translation of Autophagy Knowledge 2020; ID 9792132:1-12. https://doi.org/10.1155/2022/9792132.

Kania E., Pająk B., Orzechowski A. Calcium Homeostasis and ER Stress in Control of Autophagy. 2015; Article ID 352794: 1-12. https://doi.org/10.1155/2015/352794

Dominic P. Del Re, Dulguun Amgalan, Andreas Linkermann et al. Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease Physiol Rev. 2019; 99(4): 1765–1817 DOI: 10.1152/physrev.00022.2018.

Published

2024-01-30

How to Cite

Ковальова, О., Шапкін, В., & Іванченко, С. (2024). CELL DEATH IN HUMAN PATHOLOGY. SWorldJournal, 2(23-02), 25–31. https://doi.org/10.30888/2663-5712.2024-23-00-023

Issue

Section

Articles